Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
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چکیده
منابع مشابه
Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expression of collagen type I in cultured human liver cells as well as in liver tissue of HHcy mice. ...
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ژورنال
عنوان ژورنال: Hong Kong Journal of Nephrology
سال: 2015
ISSN: 1561-5413
DOI: 10.1016/j.hkjn.2015.09.104